In 2019,Organometallics included an article by Zhang, Chong; Zhao, Jiong-Peng; Hu, Bowen; Shi, Jing; Chen, Dafa. Recommanded Product: (4-Bromophenyl)methanol. The article was titled ãRuthenium-Catalyzed β-Alkylation of Secondary Alcohols and α-Alkylation of Ketones via Borrowing Hydrogen: Dramatic Influence of the Pendant N-Heterocycleã? The information in the text is summarized as follows:
Three bidentate ruthenium(II) complexes with a pyridonate fragment I (1-3; R = Ph, 2-thienyl, 2-thiazolyl) were prepared and fully characterized. These complexes are structurally similar, but differ in their pendant substituents. Complex 1 contains a Ph unit, whereas complexes 2 and 3 have uncoordinated thienyl and thiazolyl groups, resp. These complexes were tested as catalysts for β-alkylation of secondary alcs. ArCH(OH)Me (Ar = Ph, 4-ClC6H4, 4-MeOC6H4) with primary alcs. R1CH2OH (R1 = aryl, Cy, Bu), giving benzyl alcs. ArCH(OH)CH2CH2R1 and 3 shows the highest activity, suggesting the thiazolyl ring participates in the catalytic process. Furthermore, 3 is an excellent catalyst for α-alkylation of ketones with primary alcs. Various α-alkylated ketones were synthesized in high yields, by using 0.05 mol % 3 and 0.25 equiv of t-BuOK within 30 min. In the experiment, the researchers used (4-Bromophenyl)methanol(cas: 873-75-6Recommanded Product: (4-Bromophenyl)methanol)
(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Recommanded Product: (4-Bromophenyl)methanol It undergoes efficient trimethylsilylation reaction with 1,1,1,3,3,3-hexamethyldisilazane in the presence of catalytic amount of aspartic acid in acetonitrile.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts