The author of ãIron-Catalyzed Tandem Three-Component Alkylation: Access to α-Methylated Substituted Ketonesã?were Bettoni, Leo; Seck, Charlotte; Mbaye, Mbaye Diagne; Gaillard, Sylvain; Renaud, Jean-Luc. And the article was published in Organic Letters in 2019. Electric Literature of C7H7BrO The author mentioned the following in the article:
The borrowing hydrogen strategy has been applied in the synthesis of α-branched methylated ketones via a tandem three-component reaction catalyzed by a diaminocyclopentadienone iron tricarbonyl complex. Various alkyl and aromatic Me ketones underwent dialkylation with various primary alcs. and methanol as alkylating agents in mild reaction conditions and good yields. Deuterium labeling experiments suggested that the benzylic alc. was the hydrogen source in this tandem process. The results came from multiple reactions, including the reaction of (4-Bromophenyl)methanol(cas: 873-75-6Electric Literature of C7H7BrO)
(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Electric Literature of C7H7BrO It undergoes oxidation reaction in the presence of polyvinylpolypyrrolidone-supported hydrogen peroxide, silica sulfuric acid and ammonium bromide to yield 4-bromobenzaldehyde.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts