Gu, Shunyan; Chen, Junqi; Musgrave, Charles B.; Gehman, Zoe M.; Habgood, Laurel G.; Jia, Xiaofan; Dickie, Diane A.; Goddard, William A.; Gunnoe, T. Brent published their research in Organometallics in 2021. The article was titled ãFunctionalization of RhIII-Me Bonds: Use of “”Capping Arene”” Ligands to Facilitate Me-X Reductive Eliminationã?Recommanded Product: 7748-36-9 The article contains the following contents:
Authors show how to improve the yield of MeX from CH4 activation catalysts from 12% to 90% through the use of “”capping arene”” ligands. Four (FP)RhIII(Me)(TFA)2 {FP = “”capping arene”” ligands, including 8,8′-(1,2-phenylene)diquinoline (6-FP), 8,8′-(1,2-naphthalene)diquinoline (6-NPFP), 1,2-bis(N-7-azaindolyl)benzene (5-FP), and 1,2-bis(N-7-azaindolyl)naphthalene (5-NPFP)} complexes. These complexes and (dpe)RhIII(Me)(TFA)2 (dpe = 1,2-di-2-pyridylethane) were synthesized and tested for their performance in reductive elimination of MeX (X = TFA or halide). The FP ligands were used with the goal of blocking a coordination site to destabilize the RhIII complexes and facilitate MeX reductive elimination. On the basis of single-crystal x-ray diffraction studies, the 6-FP and 6-NPFP ligated Rh complexes have Rh-arene distances shorter than those of the 5-FP and 5-NPFP Rh complexes; thus, it is expected that the Rh-arene interactions are weaker for the 5-FP complexes than for the 6-FP complexes. Consistent with authors hypothesis, the 5-FP and 5-NPFP RhIII complexes demonstrate improved performance (from 12% to ~60% yield) in the reductive elimination of MeX. The reductive elimination of MeX from (FP)RhIII(Me)(TFA)2 can be further improved by the use of chem. oxidants. For example, the addition of 2 equivalent of AgOTf leads to 87(2)% yield of MeTFA and can be achieved in CD3CN at 90° using (5-FP)Rh(Me)(TFA)2. The experimental process involved the reaction of Oxetan-3-ol(cas: 7748-36-9Recommanded Product: 7748-36-9)
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