ãE- and Z-, di- and tri-substituted alkenyl nitriles through catalytic cross-metathesisã?was written by Mu, Yucheng; Nguyen, Thach T.; Koh, Ming Joo; Schrock, Richard R.; Hoveyda, Amir H.. COA of Formula: C6H12OThis research focused onunsaturated nitrile diastereoselective stereoretentive preparation; molybdenum catalyst stereoretentive cross metathesis alkene acrylonitrile maleonitrile fumaronitrile; pinacolborane isopropylphenylborane protecting group oleic alc acid cross metathesis. The article conveys some information:
Molybdenum alkylidene complexes (either molybdenum-based monoaryloxide pyrrolides or chlorides) were used as catalysts for the diastereoselective olefin metathesis reactions of alkenes with acrylonitrile, maleonitrile, or fumaronitrile to provide (E)- or (Z)-α,β-unsaturated nitriles and trisubstituted α,β-unsaturated nitriles. Oleyl alc. and oleic acid underwent stereoselective cross-metathesis with maleonitrile using pinacolborane or bis(triisopropylphenyl)borane as in-situ protecting group reagents. Intermediates toward the synthesis of natural products and pharmaceuticals were prepared using these methods. In the experiment, the researchers used many compounds, for example, 5-Hexen-1-ol(cas: 821-41-0COA of Formula: C6H12O)
5-Hexen-1-ol(cas: 821-41-0) is used in cyclization to a tetrahydropyran by phenylselenoetherification. It is also used as a building block in synthetic chemistry.COA of Formula: C6H12O
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