Ishida, Naoki’s team published research in Organic Letters in 2012 | CAS: 18621-18-6

Azetidin-3-ol hydrochloride(cas:18621-18-6) is one of azetidine.Azetidines (azacyclobutanes) constitute a well-known class of heterocyclic compounds. Azetidine scaffold has been discovered in several natural products.Application of 18621-18-6 Several pharmacologically important synthetic compounds also contain azetidine ring. Because of inherent ring strain, the synthesis of azetidines is a challenging endeavor.

In 2012,Ishida, Naoki; Yuhki, Tatsuya; Murakami, Masahiro published 《Synthesis of Enantiopure Dehydropiperidinones from α-Amino Acids and Alkynes via Azetidin-3-ones》.Organic Letters published the findings.Application of 18621-18-6 The information in the text is summarized as follows:

Chiral dehydropiperidinones were synthesized in enantiopure form from α-amino acids and alkynes via nickel-catalyzed insertion into azetidin-3-one intermediates. After reading the article, we found that the author used Azetidin-3-ol hydrochloride(cas: 18621-18-6Application of 18621-18-6)

Azetidin-3-ol hydrochloride(cas:18621-18-6) is one of azetidine.Azetidines (azacyclobutanes) constitute a well-known class of heterocyclic compounds. Azetidine scaffold has been discovered in several natural products.Application of 18621-18-6 Several pharmacologically important synthetic compounds also contain azetidine ring. Because of inherent ring strain, the synthesis of azetidines is a challenging endeavor.

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Alcohols – Chemistry LibreTexts