On July 31, 2022, Chen, Zhou; Fei, Kangqing; Hu, Yangfan; Xu, Xiangyang; Gao, Xiao-Dong; Li, Zijie published an article.Application In Synthesis of 2,3-Dihydroxypropanoic acid The title of the article was Identification of a Novel Alditol Oxidase from Thermopolyspora flexuosa with Potential Application in D-Glyceric Acid Production. And the article contained the following:
Abstract: Glycerol is a potential sustainable feedstock, and biorefining processes to convert glycerol into value-added chems. have been developed over the past decade. Alditol oxidase (AldO) is capable of selectively oxidizing the primary hydroxyl groups of alditols such as glycerol. In this study, a new FAD-binding protein from Thermopolyspora flexuosa was expressed and identified as a novel alditol oxidase (AldOT.聽fle). AldOT.聽fle displayed the optimal activity at pH 8.0 and 25 掳C. AldOT.聽fle was not metal-dependent, but the activity was completely inhibited by Fe3+. AldOT.聽fle had a wide substrate specificity and high catalytic efficiency for glycerol. Furthermore, the recombinant AldOT.聽fle could produce D-glyceric acid from glycerol with a conversion rate ranging from 86.6% (5 mM glycerol) to 20.5% (500 mM glycerol). The recombinant E. coli with AldOT.聽fle could also produce 23.8 mM D-glyceric acid from 100 mM glycerol. The recombinant AldOT.聽fle had the potential to produce other aldehyde products by selectively oxidizing the hydroxyl groups of alditols and many other commodity chems. by redesigning glycerol metabolism The experimental process involved the reaction of 2,3-Dihydroxypropanoic acid(cas: 473-81-4).Application In Synthesis of 2,3-Dihydroxypropanoic acid
The Article related to alditol oxidase, d-glyceric acid, glycerol, actinobacteria, escherichia coli: genetics, escherichia coli: metabolism, glyceric acids, glycerol: metabolism, oxidoreductases: genetics, sugar alcohols and other aspects.Application In Synthesis of 2,3-Dihydroxypropanoic acid
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