On September 30, 1997, Bazylak, Grzegorz; Aboul-Enein, Hassan Y. published an article.Product Details of 2160-93-2 The title of the article was Chemometric account for retention of lysosomotropic alkanolamines in planar chromatography systems. And the article contained the following:
Planar chromatog. retention data (in form of thermodynamically meaningful RM coefficients) for twelve model alkanolamines, indicating lysosomotropic activity, were determined in eighty chromatog. systems using eight different silica gel layers with varied chem. bonded stationary phases. In performed TLC experiments, aqueous binary mobile phases containing methanol or acetonitrile as organic modifier, in five different proportions, were applied. Addnl., nine quantum chem. descriptors were calculated for test solutes by a semi-empirical mol. modeling procedure (AM1) to describe their structural properties. Chemometric technique by the multivariate method of principal components anal. (PCA) was applied to the all completed chromatog. retention and computational chem. data for identification of the most selective and useful planar chromatog. systems as well as mol. interactions of solutes which affect their retention phenomena in the particular separation mode. The statistically significant relationship was revealed between quant. measure of antimicrobial activity of alkanolamines and values of calculated scores of principal components. The experimental process involved the reaction of 2,2′-(tert-Butylazanediyl)diethanol(cas: 2160-93-2).Product Details of 2160-93-2
The Article related to alkanol amine lysosomotropic chemometry planar chromatog, Pharmacology: Methods and other aspects.Product Details of 2160-93-2
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