In 2019,RSC Advances included an article by Abdolmohammadi, Shahrzad; Mirza, Behrooz; Vessally, Esmail. Safety of 3-Hydroxybenzaldehyde. The article was titled 《Immobilized TiO2 nanoparticles on carbon nanotubes: an efficient heterogeneous catalyst for the synthesis of chromeno[b]pyridine derivatives under ultrasonic irradiation》. The information in the text is summarized as follows:
A new protocol for the synthesis of chromeno[b]pyridine derivatives was described via a three-component reaction of 4-aminocoumarin, aromatic aldehydes and malononitrile catalyzed by TiO2 nanoparticles immobilized on carbon nanotubes (TiO2-CNTs) as an efficient heterogeneous catalyst under ultrasonic irradiation in water. The sustainable and economic benefits of the protocol were the high yields of products, short reaction time, simple work-up procedure, and use of a non-toxic and reusable catalyst.3-Hydroxybenzaldehyde(cas: 100-83-4Safety of 3-Hydroxybenzaldehyde) was used in this study.
3-Hydroxybenzaldehyde(cas: 100-83-4) can be used as a reactant along with ethyl acetoacetate and thiourea in the synthesis of corresponding dihydropyrimidine-2-thione (monastrol), using Yb(OTf)3 as a catalyst by Biginelli cyclocondensation reaction.Safety of 3-Hydroxybenzaldehyde
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts