Application of 5259-98-3, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 5259-98-3, name is 5-Chloropentan-1-ol, molecular formula is C5H11ClO, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
Under a nitrogen atmosphere, 5.0 g of the compound represented by the formula (I-8-12), 0.2 g of pyridinium p-toluenesulfonate and 30 mL of dichloromethane were added to the reaction vessel. 3.8 g of 3,4-dihydro-2H-pyran was added with ice cooling and the mixture was stirred. After washing with a saturated aqueous solution of sodium bicarbonate and brine, purification was carried out by column chromatography (alumina, dichloromethane) to obtain 7.6 g of the compound represented by the formula (I-8-13).
According to the analysis of related databases, 5259-98-3, the application of this compound in the production field has become more and more popular.
Reference:
Patent; DIC CORPORATION; HORIGUCHI, MASAHIRO; AOKI, YOSHIO; HAYASHI, TAKUO; TSURUTA, TORU; (69 pag.)JP2017/218391; (2017); A;,
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