Usuki, Toyonobu; Komatsu, Akira published an article in Tetrahedron Letters. The title of the article was 《Preparation of monoalkylpiperidines via the mild hydrogenation of monoalkynylpyridines》.Recommanded Product: 93524-95-9 The author mentioned the following in the article:
Monoalkynylpyridines were prepared via a Sonogashira cross-coupling reaction between monoiodopyridines and alkynes. From the obtained monoalkynylpyridines, mild hydrogenation was conducted to produce the corresponding monoalkylpiperidines in moderate to excellent yields. The hydrogenation reaction was carried out under H2(1 atm) in the presence of 10 wt% Pd/C (5 equiv) in either AcOH or MeOH at room temperature Therefore, this mild method was useful for the quick and easy preparation of monoalkylpiperidines. The results came from multiple reactions, including the reaction of 3-(4-Pyridyl)-2-propyn-1-ol(cas: 93524-95-9Recommanded Product: 93524-95-9)
3-(4-Pyridyl)-2-propyn-1-ol(cas: 93524-95-9) belongs to pyridine. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. As ligands, solvents, and catalysts they facilitate reactions; thus descriptions of these new ligands and their applications abound each year.Recommanded Product: 93524-95-9
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