《Amino-Acid-Mediated Aerobic Oxidation of Organoborons for the Synthesis of Phenolic Derivatives Using Single Electron Transfer》 was published in ChemistrySelect in 2020. These research results belong to Gujjarappa, Raghuram; Vodnala, Nagaraju; Garg, Aakriti; Hazra, Chinmoy K.; Gupta, Sreya; Malakar, Chandi C.. Computed Properties of C6H7BO3 The article mentions the following:
An efficient amino-acid-mediated ipso-hydroxylation of arylboronic acids, aryl boronate esters and aryl trifluoroborates RX (R = 4-chlorophenyl, naphthalen-1-yl, quinolin-5-yl, etc.; X = BF3K, B(OH)2, Bpin) to aryl alcs. ROH has been described. The current protocol was realized by using sub-stoichiometric amount of L-histidine in presence of triethylamine under aerobic conditions in DMF as solvent. This amino-acid-mediated process provides an alternative route for the hydroxylation of organoborons through in situ generation of hydrogen peroxide. The present protocol explores the synthetic utility of amino acids as organocatalysts for the preparation of aryl alcs. It was observed that L-histidine plays an important role for the conversion of aerial oxygen into hydrogen peroxide via thermal excitation process followed by thermal degradation of Et3N. The developed approach holds good for a wide range of compounds with excellent yields and competent functional group tolerance. The experimental process involved the reaction of 2-Hydroxyphenylboronic acid(cas: 89466-08-0Computed Properties of C6H7BO3)
2-Hydroxyphenylboronic acid(cas: 89466-08-0) belongs to acyl phenylboronic acid. Phenylboronic acid (PBA) has been used to extract β-blockers (a class of aminoalcohol-containing drugs) from aqueous solution, rat, and human plasma. Computed Properties of C6H7BO3
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