In 2022,Hu, Chunyang; Chen, Fangming; Lu, Guo-Ping; Yi, Wen-Bin published an article in Chinese Chemical Letters. The title of the article was 《Deuterated N-difluoromethylthiophthalimide: A stable, scalable reagent for radical and electrophilic deuteriodifluoromethylthiolations》.Related Products of 7748-36-9 The author mentioned the following in the article:
A new, stable and scalable reagent for deuteriodifluoromethylthiolation (deuterated N-difluoromethylthiophthalimide, PhthSCF2D) has been developed. This reagent can be applied for the photocatalytic radical deuteriodifluoromethylthiolation of various olefins and aldehydes (30 examples). Meanwhile, it can achieve the electrophilic deuteriodifluoromethylthiolation of a series of electrophilic substrates including electron-rich arenes, aryl/vinylboronicacids, alkynes, amines, thiols and β-ketoesters (22 examples). Some complex mols. can also be applied in both radical and electrophilic deuteriodifluoromethylthiolation using PhthSCF2D as the reagent. In the experiment, the researchers used Oxetan-3-ol(cas: 7748-36-9Related Products of 7748-36-9)
Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.Related Products of 7748-36-9
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