Ingale, Ajit P.; Shinde, Sandeep V.; Thorat, Nitin M. published their research in Synthetic Communications in 2021. The article was titled 《Sulfated tungstate: A highly efficient, recyclable and ecofriendly catalyst for chemoselective N-tert butyloxycarbonylation of amines under the solvent-free conditions》.Name: 3-Aminopropan-1-ol The article contains the following contents:
Sulfated tungstate catalyzed an efficient and ecofriendly protocol was described for the chemoselective N-tert-butyloxycarbonylation of amines under the solvent-free conditions at room temperature The variety of functionalized aliphatic, aromatic and heteroaromatic amines efficiently underwent the N-tert-butyloxycarbonylation under the developed protocol. The aminoalc., aminophenol, aminoester as well as various chiral amines underwent the chemoselective N-Boc protection under the optimized reaction condition. The rapid reaction rate, mild conditions, very good functional group tolerance, excellent yield, solvent-free, easy recovery products and excellent catalyst recyclability were the advantages of this protocol. This made the protocol feasible, economical and environmentally benign. In the experimental materials used by the author, we found 3-Aminopropan-1-ol(cas: 156-87-6Name: 3-Aminopropan-1-ol)
3-Aminopropan-1-ol(cas: 156-87-6) belongs to anime. The reaction of alkyl halides, R―X, where X is a halogen, or analogous reagents with ammonia (or amines) is useful with certain compounds. Not all alkyl halides are effective reagents; the reaction is sluggish with secondary alkyl groups and fails with tertiary ones. Its usefulness is largely confined to primary alkyl halides (those having two hydrogen atoms on the reacting site).Name: 3-Aminopropan-1-ol
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