Ingale, Ajit P.; Ukale, Dattatraya; Garad, Dnyaneshwar N.; Shinde, Sandeep V. published their research in Synthetic Communications in 2021. The article was titled 《Nanoceria as an efficient and green catalyst for the chemoselective N-tert-butyloxycarbonylation of amines under the solvent-free conditions》.Reference of 3-Aminopropan-1-ol The article contains the following contents:
Nanocerium oxide mediated an efficient and green protocol has been described for the chemoselective N-tert-butyloxycarbonylation of amines under the solvent-free conditions at ambient temperature Various aliphatic, aromatic and heteroaromatic amines were protected using developed protocol and several functional groups such as alc., phenol and ester were well tolerated under these conditions. The rapid reaction rate, mild conditions, very good functional group tolerance, excellent yield, solvent-free, easy recovery products and excellent catalyst recyclability are the advantages of this protocol. This makes the protocol feasible, economical and environmentally benign. The experimental process involved the reaction of 3-Aminopropan-1-ol(cas: 156-87-6Reference of 3-Aminopropan-1-ol)
3-Aminopropan-1-ol(cas: 156-87-6) belongs to anime. Hydrogen peroxide (H2O2) and peroxy acids generally add an oxygen atom to the nitrogen of amines. With primary amines, this step is normally followed by further oxidation, leading to nitroso compounds, RNO, or nitro compounds, RNO2. Secondary amines are converted to hydroxylamines, R2NOH, and tertiary amines to amine oxides, R3NO.Reference of 3-Aminopropan-1-ol
Referemce:
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