In 2022,Hall, Ryan C.; Qin, Jingcan; Laney, Victoria; Ayat, Nadia; Lu, Zheng-Rong published an article in ACS Applied Bio Materials. The title of the article was 《Manganese(II) EOB-Pyclen Diacetate for Liver-Specific MRI》.Quality Control of 2,6-Pyridinedimethanol The author mentioned the following in the article:
MRI is increasingly utilized for the diagnosis of liver disease and focal liver lesions. Although liver-targeted gadolinium-based contrast agents (GBCAs) have high efficacy, there continue to be safety concerns regarding release of toxic Gd(III) ions. Herein, Mn(EOB-PC2A) is synthesized as a nongadolinium alternative for liver-specific MRI. Mn(EOB-PC2A) has an r1 relaxivity of 2.8 mM-1 s-1 in Dulbecco’s phosphate-buffered saline (DPBS) and 5.9 mM-1 s-1 in saline containing human serum albumin at 1.5 T. It has a strong uptake in hepatocytes with minimal toxicity and demonstrated robust liver-specific enhancement at a dose of 60 μmol/kg. Mn(EOB-PC2A) is a promising liver-specific contrast agent for liver MRI. In the experimental materials used by the author, we found 2,6-Pyridinedimethanol(cas: 1195-59-1Quality Control of 2,6-Pyridinedimethanol)
2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridine is a relatively complex molecule and exhibits a number of different bands in IR spectra. Among others, the bands characterizing the ν8a and ν19b modes have been found to be sensitive to the coordination or protonation of the molecule. Note that the band that is diagnostic for the PyH+ ion at about 1545 cm− 1 (ν19b mode) does not overlap with any of the other bands.Quality Control of 2,6-Pyridinedimethanol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts