Electric Literature of C3H9NOIn 2020 ,《Synthesis, Characterization, Antibacterial Properties and DFT Studies of Two New Polypyrazolic Macrocycles》 was published in Polycyclic Aromatic Compounds. The article was written by Harit, Tarik; Cherfi, Mounir; Abouloifa, Houssam; Isaad, Jalal; Bouabdallah, Ibrahim; Rahal, Mahmoud; Asehraou, Abdeslam; Malek, Fouad. The article contains the following contents:
Two novel sym. macrocycles I [R = CHMe2, (CH2)3OH] containing four pyrazolic units, with two different side arms were synthesized and characterized. Their antibacterial activity was investigated by determining the inhibition zone diameter in agar gel and minimal inhibitory concentration The obtained results showed that the tetrapyrazolic macrocycle with a hydroxyl group in its side chain presented the best inhibitory effect against all tested bacterial strain. Mol. geometries, HOMO-LUMO anal. and mol. electrostatic potential of macrocycles were investigated by theor. calculations with B3LYP/6-31G* level. The mol. electrostatic potential surface showed that the presence of electrophile site in the lateral arms of these macrocycles enhances the antibacterial activity of such compounds In addition to this study using 3-Aminopropan-1-ol, there are many other studies that have used 3-Aminopropan-1-ol(cas: 156-87-6Electric Literature of C3H9NO) was used in this study.
3-Aminopropan-1-ol(cas: 156-87-6) belongs to anime. Amines have a free lone pair with which they can coordinate to metal centers. Amine–metal bonds are weaker because amines are incapable of backbonding, but they are still important for sensing applications.While stronger than hydrogen bonds, amine–metal bonds are still weaker than both covalent and ionic bonds.Electric Literature of C3H9NO
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