Mavel, Sylvie; Renou, Jean Louis; Galtier, Christophe; Snoeck, Robert; Andrei, Graciela; Balzarini, Jan; De Clercq, Erik; Gueiffier, Alain published an article in 2001, the title of the article was Synthesis of imidazo[1,2-a]pyridine derivatives as antiviral agents.SDS of cas: 72364-46-6 And the article contains the following content:
The synthesis and antiviral activity of original dibromoimidazo[1,2-a]pyridines bearing a thioether side chain was reported. Mol. modeling was used to identify biophoric structural patterns that are common to the 16 compounds Structure-activity relationship (SAR) studies identified hydrophobicity as the most important factor for activity. From these SAR studies, the antiviral activity could be predicted. The experimental process involved the reaction of (2-Fluorophenyl)methanethiol(cas: 72364-46-6).SDS of cas: 72364-46-6
The Article related to imidazopyridine derivative formation antiviral activity, Pharmacology: Structure-Activity and other aspects.SDS of cas: 72364-46-6
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