Sohtun, Winaki P. et al. published their research in Journal of Inorganic Biochemistry in 2021 |CAS: 96-76-4

The Article related to phenoxazinone synthase mimics copper coordination complex, copper(ii) complexes, multicopper oxidases, reaction mechanism, synthase like-activity, Placeholder for records without volume info and other aspects.Recommanded Product: 96-76-4

On March 31, 2021, Sohtun, Winaki P.; Muthuramalingam, Sethuraman; Sankaralingam, Muniyandi; Velusamy, Marappan; Mayilmurugan, Ramasamy published an article.Recommanded Product: 96-76-4 The title of the article was Copper(II) complexes of tripodal ligand scaffold (N3O) as functional models for phenoxazinone synthase. And the article contained the following:

The copper(II) complexes [Cu(L)NO3] (1-9) of newer N3O ligands (L1-L9) have been synthesized and characterized. The mol. structure of 1, 4, and 7 exhibited nearly a perfect square pyramidal geometry (τ, 0.04-0.11). The Cu-OPhenolate bonds (∼ 1.91 Å) are shorter than the Cu–N bonds (∼ 2.06 Å) due to the stronger coordination of anionic phenolate oxygen. The Cu(II)/Cu(I) redox potentials of 1-9 appeared around -0.102 to -0.428 V vs. Ag/Ag+ in water. The electronic spectra of the complexes showed the d-d transitions around 643-735 nm and axial EPR parameter (g||, 2.243-2.270; A||, 164-179 x 10-4 cm-1) that corresponds to square pyramidal geometry. The bonding parameters α2, 0.760-0.825; β2, 0.761-0.994; γ2, 0.504-0.856 and K||, 0.698-0.954 and K⊥, 0.383-0.820 calculated from EPR spectra and energies of d-d transitions. The complexes catalyzed the conversion of substrate 2-aminophenol into 2-aminophenoxazine-3-one using mol. oxygen in the water and exhibited the yields of 41-61%. The formation of the product is accomplished by the appearance of a new absorption band at 430 nm and the rates of formation were calculated as 6.98-15.65 x 10-3 s-1 in water. The reaction follows Michaelis-Menten enzymic reaction kinetics with turnover numbers (kcat) 9.11 x 105 h-1 for 1 and 4.66 x 105 h-1 for 9 in water. The spectral, redox and kinetic studies were performed in water to mimic the enzymic oxidation reaction conditions. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Recommanded Product: 96-76-4

The Article related to phenoxazinone synthase mimics copper coordination complex, copper(ii) complexes, multicopper oxidases, reaction mechanism, synthase like-activity, Placeholder for records without volume info and other aspects.Recommanded Product: 96-76-4

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