On December 31, 2021, Marchesini, Paula; Lemos, Ari Sergio de Oliveira; Bitencourt, Ricardo de Oliveira Barbosa; Fiorotti, Jessica; Angelo, Isabele da Costa; Fabri, Rodrigo Luiz; Costa-Junior, Livio Martins; Lopes, Welber Daniel Zaneti; Bittencourt, Vania Rita Elias Pinheiro; Monteiro, Caio published an article.Reference of 2,4-Di-tert-butylphenol The title of the article was Assessment of lipid profile in fat body and eggs of Rhipicephalus microplus engorged females exposed to (E)-cinnamaldehyde and α-bisabolol, potential acaricide compounds. And the article contained the following:
In the present study, the lipid profile from the fat body and eggs of Rhipicephalus microplus was evaluated after exposure of engorged females to (E)-cinnamaldehyde and α-bisabolol, substances which have acaricide potential according to the literature. Engorged females collected from artificially infested cattle were immersed in a concentration of 10.0 mg/mL of each substance. Dissection of the female fat bodies was performed at different times (72 h and 120 h), for subsequent lipid extraction In addition, on the fifth day of oviposition, were collected 50.0 mL50.0 mL aliquots of the egg mass of each treatment to perform the same lipid extraction procedure. To assess the lipid profiles, the samples were submitted to the thin layer chromatog. (TLC) and gas chromatog.-mass spectrometry (GC-MS) anal. Furthermore, an in silico anal. was performed using PASS online software to predict the possible mol. targets of (E)-cinnamaldehyde and α-bisabolol. As result, the main lipids identified from the fat body were triacylglycerides, fatty acids, and cholesterol, whereas, triacylglycerides (TAG), fatty acids (FA), and cholesterol (CHO) and cholesterol esters (CHOE), were identified in the eggs. The results also showed a significant increase (p < 0.05) of CHO in the fat body in the group exposed to (E)-cinnamaldehyde at 72 h (0.12 μg/fat body) and 120 h (0.46 μg/fat body), in the eggs from females treated with this same substance, there was a significant reduction (p < 0.05) in the amount of CHO (0.21 μg), compared to the water control group (0.45 μg). In the GC-MS technique, 5 chem. classes were found, and variations were observed between these substances, mainly hydrocarbons and steroids, in the different groups, and (E)-cinnamaldehyde promoted the greatest changes. From the predictions of the in silico study, 38 and 20 targets were selected, resp., which are mainly related to alterations in lipid metabolism, immune system and nervous system. This study provides the first report of changes in lipid metabolism of R. microplus exposed to (E)-cinnamaldehyde and α-bisabolol, as well as presenting possible activity on the mol. targets of these substances, expanding knowledge for the potential use of these compounds in the development of botanical acaricides. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Reference of 2,4-Di-tert-butylphenol
The Article related to rhipicephalus tetradecane pentadecane hexadecane cinnamaldehyde alpha bisabolol, cattle tick, energetic metabolism, essential oil, phenylpropanoid, terpene, Placeholder for records without volume info and other aspects.Reference of 2,4-Di-tert-butylphenol
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