On December 31, 2020, Ahmadi, Delaram; Mahmoudi, Najet; Li, Peixun; Ma, Kun; Doutch, James; Foglia, Fabrizia; Heenan, Richard K.; Barlow, David; Lawrence, M. Jayne published an article.Application of 111-29-5 The title of the article was Revealing the Hidden Details of Nanostructure in a Pharmaceutical Cream. And the article contained the following:
Creams are multi-component semi-solid emulsions that find widespread utility across a wide range of pharmaceutical, cosmetic, and personal care products, and they also feature prominently in veterinary preparations and processed foodstuffs. The internal architectures of these systems, however, have to date been inferred largely through macroscopic and/or indirect exptl. observations and so they are not well-characterized at the mol. level. Moreover, while their long-term stability and shelf-life, and their aesthetics and functional utility are critically dependent upon their mol. structure, there is no real understanding yet of the structural mechanisms that underlie the potential destabilizing effects of additives like drugs, anti-oxidants or preservatives, and no structure-based rationale to guide product formulation. In the research reported here we sought to address these deficiencies, making particular use of small-angle neutron scattering and exploiting the device of H/D contrast variation, with complementary studies also performed using bright-field and polarised light microscopy, small-angle and wide-angle X-ray scattering, and steady-state shear rheol. measurements. Through the convolved findings from these studies we have secured a finely detailed picture of the mol. structure of creams based on Aqueous Cream BP, and our findings reveal that the structure is quite different from the generic picture of cream structure that is widely accepted and reproduced in textbooks. The experimental process involved the reaction of Pentane-1,5-diol(cas: 111-29-5).Application of 111-29-5
The Article related to cosmetics nanostructure pharmaceutical cream, Pharmaceuticals: Formulation and Compounding and other aspects.Application of 111-29-5
Referemce:
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Alcohols – Chemistry LibreTexts