On December 24, 2003, Polla, Magnus published a patent.Safety of 2-(Methylamino)ethan-1-ol hydrochloride The title of the patent was Preparation of 2,5-disubstituted 3-mercaptopentanoic acids as carboxypeptidase U inhibitors. And the patent contained the following:
The title compounds R1(CH2)2CH(SH)CH(CO2H)CH2R2 [I; R1 = (un)substituted Ph, naphthyl, pyridinyl, etc.; R2 = aminopyridinyl, aminothiazolyl, 3-azabicyclo[3.2.1]octyl] which inhibit carboxypeptidase U and thus can be used in the prevention and treatment of diseases where inhibition of carboxypeptidase U is beneficial, were prepared E.g., a 4-step synthesis of 2-[(6-aminopyridin-3-yl)methyl]-5-(1,1′-biphenyl-3-yl)-3-mercaptopentanoic acid (starting from 3-iodo-1,1′-biphenyl), was given. Biol. data was given for 13 exemplified compounds I. In further aspects, the invention relates to pharmaceutical compositions containing at least one compound I. The experimental process involved the reaction of 2-(Methylamino)ethan-1-ol hydrochloride(cas: 62640-03-3).Safety of 2-(Methylamino)ethan-1-ol hydrochloride
The Article related to mercaptopentanoate aminopyridinylmethyl preparation carboxypeptidase u inhibitor, Heterocyclic Compounds (One Hetero Atom): Pyridines and other aspects.Safety of 2-(Methylamino)ethan-1-ol hydrochloride
Referemce:
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Alcohols – Chemistry LibreTexts