On February 22, 2017, Zhao, Fulu; Wang, Qi; Wang, Yinhu; Li, Sen; Wang, Lichun; Wang, Jingyi published a patent.Related Products of 428855-17-8 The title of the patent was Intermediate compound of LB80380 drug and preparation method and application thereof. And the patent contained the following:
The invention provides an intermediate compound of LB80380 represented by formula I, wherein R1, R2, R3 and R4 are independently selected from linear or branched-chain alkyl, benzyl substituted with 1-5 R5 groups and R5CO, and are the same or different, and R5 is selected from H, substituted or unsubstituted C1-C4 alkoxy, C3-C7 alkenyl alkoxy and substituted or unsubstituted benzyloxy. The invention also provides a method for preparing the compound and application of the compound When the compound was used for preparing compound 3-[({1-[(2-amino-9H-purin-9-yl) methyl]cyclopropyl}oxy) methyl]-8,8-dimethyl-3,7-dioxo-2,4,6-trioxa-3λ-phosphanonan-yl-pivalate;, the reaction route has easily available low-cost raw materials and intermediate, low cost and high safety, and is suitable for industrial production The experimental process involved the reaction of 1-[(Dibenzylamino)methyl]cyclopropanol(cas: 428855-17-8).Related Products of 428855-17-8
The Article related to lb80380 drug intermediate preparation, Organometallic and Organometalloidal Compounds: Phosphorus Compounds and other aspects.Related Products of 428855-17-8
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts