On October 15, 1981, Jacobi, Haireddin; Opitz, Wolfgang published a patent.Synthetic Route of 72364-46-6 The title of the patent was S-Alkyl 3-(alkylthio)thiopropionates and their use in drugs. And the patent contained the following:
R1SCH2CH2C(O)SR [R, R1 = alkyl optionally substituted with amino, aryl, heteroaryl, etc., (in turn optionally substituted with 1-3 halo, alkyl, nitro, alkoxy, etc.), cycloalkyl] were prepared as inflammation inhibitors (no data). Thus 0.81 mL CH2:CHCOCl was added in portions to 4.28 g 3,4,5-(MeO)3C6H2CH2SH and 8 mL 5% NaOH at room temperature, and the mixture was stirred to the end of the exotherm to give 32.1% I. The experimental process involved the reaction of (2-Fluorophenyl)methanethiol(cas: 72364-46-6).Synthetic Route of 72364-46-6
The Article related to thio ester aralkyl antiinflammatory, propionate thio benzyl antiinflammatory, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Esters, Acyl Peroxides, Acyl Halides and other aspects.Synthetic Route of 72364-46-6
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts