Bains, Amreen K.; Kundu, Abhishek; Maiti, Debabrata; Adhikari, Debashis published an article in 2021, the title of the article was Ligand-redox assisted nickel catalysis toward stereoselective synthesis of (n+1)-membered cycloalkanes from 1,n-diols with methyl ketones.Computed Properties of 111-29-5 And the article contains the following content:
A well-defined, bench-stable nickel catalyst was presented here, that can facilitate double alkylation of a Me ketone to realize a wide variety of cycloalkanes. The performance of the catalyst depends on the ligand redox process comprising an azo-hydrazo couple. The source of the bis electrophile in this double alkylation was a 1,n-diol, so that (n+1)-membered cycloalkanes can be furnished in a stereoselective manner. The reaction followed a cascade of dehydrogenation/hydrogenation reactions and adopted a borrowing hydrogen (BH) method. A thorough mechanistic anal. including the interception of key radical intermediates and DFT calculations supported the ligand radical-mediated dehydrogenation and hydrogenation reactions, which is quite rare in BH chem. In particular, this radical-promoted hydrogenation was distinctly different from conventional hydrogenations involving a metal hydride and complementary to the ubiquitous two-electron driven dehydrogenation/hydrogenation reactions. The experimental process involved the reaction of Pentane-1,5-diol(cas: 111-29-5).Computed Properties of 111-29-5
The Article related to acetophenone diol nickel catalyst diastereoselective alkylation tandem dehydrogenation hydrogenation, cycloalkyl phenyl methanone preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Ketones and Derivatives, Including Quinones and Sulfur Analogs and other aspects.Computed Properties of 111-29-5
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