On May 31, 2021, Swain, Sharada Prasanna; Shri, Om; Ravichandiran, V. published an article.Application In Synthesis of Pentane-1,5-diol The title of the article was Iridium and bis(4-nitrophenyl)phosphoric acid catalysed amination of diol by hydrogen-borrowing methodology for the synthesis of cyclic amine: Synthesis of clopidogrel. And the article contained the following:
The borrowing hydrogen method is an environmentally benign process for the synthesis of amines, as H2O is the side product. A new green process for the amination of diol by [Ir] catalyst and bis(4-nitrophenyl)phosphoric acid for the synthesis of cyclic amine is reported. This method was successfully applied for the synthesis of antiplatelet drug clopidogrel. The experimental process involved the reaction of Pentane-1,5-diol(cas: 111-29-5).Application In Synthesis of Pentane-1,5-diol
The Article related to clopidogrel preparation green, Heterocyclic Compounds (More Than One Hetero Atom): Fused-Ring Systems With Two Or More Hetero Atoms, No More Than One Hetero Atom Per Ring and other aspects.Application In Synthesis of Pentane-1,5-diol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts