On June 30, 2016, Sato, Takahiro; Nagayama, Sachiho; Yoshino, Yasuhiro; Inoue, Tsutomu; Kato, Hiroshige; Uda, Junichiro; Inaba, Masato; Yamoto, Noriko; Taniguchi, Tetsuya published a patent.HPLC of Formula: 386704-04-7 The title of the patent was Preparation of novel heterocyclic derivative as EPO production promoters for prevention or treatment of anemia. And the patent contained the following:
The present invention relates to a compound represented by the following general formula I [wherein X represents an oxygen atom, an imino group, a sulfur atom, sulfinyl, or sulfonyl, R1, R2, and R3 each independently represent a hydrogen atom or a C1-6 alkyl group, R4 represents a hydrogen atom, a C1-6 alkyl group, or an arylalkyl group, R5 represents an alkyl, alkenyl, alkynyl, aryl, or heteroaryl group]. This compound has excellent EPO-production acceleration activity and is useful as a pharmaceutical. Thus, addition of [5-(3,5-dichlorophenylsulfanyl)-7-hydroxy[1,2,4]triazolo[1,5-a]pyridine-8-carbonylamino]acetic acid, prepared from 3,5-dichlorobenzenethiol and 7-benzyloxy-5-iodo[1,2,4]triazolo[1,5-α]pyridine-8-carboxylic acid tert-Bu ester, to culture of Hep3B cells significantly increased erythropoietin production The experimental process involved the reaction of (6-(Trifluoromethyl)pyridin-3-yl)methanol(cas: 386704-04-7).HPLC of Formula: 386704-04-7
The Article related to heterocyclic amide compound preparation erythropoietin production promoter treatment anemia, triazolopyridinecarboxamidoacetic acid erythropoietin production promoter antianemic drug and other aspects.HPLC of Formula: 386704-04-7
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