Becker, Dominic; Kazmaier, Uli published an article in 2015, the title of the article was Synthesis of simplified halogenated chondramide derivatives with strong cytostatic properties.HPLC of Formula: 32462-30-9 And the article contains the following content:
Removing the Me groups and the stereogenic centers from the ω-hydroxy acid of the chondramides results in a significant drop in the cytotoxicity of these interesting depsipeptides. This effect can be almost compensated for by introduction of a second chlorine atom on the β-tyrosine moiety of the natural products. These simplified chondramides are much easier accessible than natural chondramides. The experimental process involved the reaction of H-Phg(4-OH)-OH(cas: 32462-30-9).HPLC of Formula: 32462-30-9
The Article related to cyclic peptide depsipeptide halogenated chondramide enantioselective synthesis antitumor agent, hydroxy acid esterification tryptophan protection amination peptide coupling cyclization and other aspects.HPLC of Formula: 32462-30-9
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