On September 30, 2022, Chung, Hyuk-Jin; Lee, Hwanhui; Kim, Myeongsun; Lee, Ji Won; Saeed, Maham; Lee, Hayera; Jung, Seung-Hee; Shim, Jae-Jung; Lee, Jung-Lyoul; Heo, Keon; Choi, Hyung-Kyoon published an article.Recommanded Product: 2,3-Dihydroxypropanoic acid The title of the article was Development and metabolic profiling of a postbiotic complex exhibiting antibacterial activity against skin microorganisms and anti-inflammatory effect on human keratinocytes. And the article contained the following:
Beyond probiotics, the interest in the application of postbiotics to various fields has been growing. We aimed to develop a novel postbiotic complex (PC) with antibacterial and anti-inflammatory properties. Through antibacterial activity testing against Staphylococcus aureus or Cutibacterium acnes, a PC [a mixture of cell-free supernatants (postbiotics) from probiotic Lactobacillus helveticus (HY7801) and Lactococcus lactis (HY449)] was developed. Anti-inflammatory activity of the PC was investigated using HaCaT keratinocytes treated with S. aureus or C. acnes. PC significantly decreased IL-8 levels and increased hyaluronic acid levels in HaCaT cells cultured with S. aureus or C. acnes. GC-MS based metabolic profiling suggested 2-hydroxyisocaproic acid, hypoxanthine, succinic acid, ornithine, and γ-aminobutyric acid as potential contributing metabolites for the antibacterial and anti-inflammatory effects of PC. The PC developed in this study could be utilized in food, cosmetics, and pharmaceutical products as an alternative or complementary resources of probiotics. The experimental process involved the reaction of 2,3-Dihydroxypropanoic acid(cas: 473-81-4).Recommanded Product: 2,3-Dihydroxypropanoic acid
The Article related to skin microorganism postbiotic antibacterial antiinflammatory human keratinocyte metabolic profiling, anti-inflammatory activity, antibacterial activity, metabolic profiling, postbiotics, probiotics and other aspects.Recommanded Product: 2,3-Dihydroxypropanoic acid
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