Simple alcohols are found widely in nature. Ethanol is the most prominent because it is the product of fermentation, a major energy-producing pathway. 16545-68-9, formula is C3H6O, Other simple alcohols, chiefly fusel alcohols, are formed in only trace amounts. More complex alcohols however are pervasive, as manifested in sugars, some amino acids, and fatty acids. , Reference of 16545-68-9
Yu, Wensheng;Deng, Yongqi;Hopkins, Brett;Huang, Xianhai;Sloman, David;Zhang, Hongjun;Li, Derun;McGowan, Meredeth A.;White, Catherine;Pu, Qinglin;Liu, Kun;Fradera, Xavier;Lesburg, Charles A.;Martinot, Theo;Doty, Amy;Ferguson, Heidi;Nickbarg, Elliott B.;Cheng, Mangeng;Geda, Prasanthi;Song, Xuelei;Smotrov, Nadya;Abeywickrema, Pravien;Andrews, Christine;Chamberlin, Chad;Mabrouk, Omar;Curran, Patrick;Richards, Matthew;Saradjian, Peter;Miller, J. Richard;Knemeyer, Ian;Otte, Karin;Vincent, Stella;Sciammetta, Nunzio;Bennett, David Jonathan;Han, Yongxin research published 《 SAR towards indoline and 3-azaindoline classes of IDO1 inhibitors》, the research content is summarized as follows. A novel series of IDO1 inhibitors have been identified with good IDO1 Hela cell and human whole blood activity. These inhibitors contain an indoline or a 3-azaindoline scaffold. Their structure-activity-relationship studies have been explored. Compounds 37 (I) and 41 (II) stood out as leads due to their good potency in IDO1 Hela assay, good IDO1 unbound hWB IC50s, reasonable unbound clearance, and good MRT in rat and dog PK studies.
Reference of 16545-68-9, Cyclopropanol is a cyclopropane in which a hydrogen atom is replaced by a hydroxy group. It is a member of cyclopropanes and an aliphatic alcohol.
Cyclopropanol is a useful research compound. Its molecular formula is C3H6O and its molecular weight is 58.08 g/mol. The purity is usually 95%.
Cyclopropanol is a cyclic organic compound that is synthesized from sodium hydroxide solution, nitrogen atoms, and carbonyl groups. Cyclopropanol has shown inhibitory effects on inflammatory bowel disease in rats. This drug also inhibits the production of hydrogen chloride and hydrochloric acid in the stomach, which can lead to ulcers. Cyclopropanol has been found to be effective against bowel diseases such as Crohn’s disease and ulcerative colitis. This drug has been shown to have strong antioxidant properties, which may be due to its ability to reduce hydroxyl radicals., 16545-68-9.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts