In general, the hydroxyl group makes alcohols polar. Those groups can form hydrogen bonds to one another and to most other compounds. 7748-36-9, formula is C3H6O2, Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. Methanol, ethanol, and propanol are miscible in water. Butanol, with a four-carbon chain, is moderately soluble. Computed Properties of 7748-36-9
Wu, Cheng-Jun;Wu, Jia-Qiang;Hu, Yunfei;Pu, Suyun;Lin, Yuying;Zeng, Zimai;Hu, Jinhui;Chen, Wen-Hua research published 《 Design, synthesis and biological evaluation of indole-based [1,2,4]triazolo[4,3-a] pyridine derivatives as novel microtubule polymerization inhibitors》, the research content is summarized as follows. A series of indole-based [1,2,4]triazolo [4,3-a]pyridine derivatives was designed and synthesized as novel microtubulin polymerization inhibitors by using a conformational restriction strategy. These compounds exhibited moderate to potent anti-proliferative activities against a panel of cancer cell lines (HeLa, A549, MCF-7 and HCT116). Among them, compound I featuring a N-methyl-5-indolyl substituent at the C-6 position of the [1,2,4]triazolo [4,3-a]pyridine core exhibited the highest antiproliferative activity with the IC50 values ranging from 15 to 69 nM, and remarkable inhibitory effect on tubulin polymerization with an IC50 value of 1.64μM. Mechanistic studies revealed that compound I induced cellular apoptosis and cell cycle arrest at the G2/M phase in a dose-dependent fashion. Moreover, compound I significantly suppressed wound closure and disturbed microtubule networks.
Computed Properties of 7748-36-9, Oxetan-3-ol is a useful research compound. Its molecular formula is C3H6O2 and its molecular weight is 74.08 g/mol. The purity is usually 95%.
Oxetan-3-ol is a synthetic hydroxy compound with the chemical formula C6H12O3. It is an organic solvent that can be used in reactions involving vinyl alcohol and oxetane, such as ring-opening polymerization and cationic polymerization. Oxetan-3-ol has also been shown to react with ethyl bromoacetate to form the corresponding oxetane, which can be used as a bioisostere for chloropropane, a potential replacement for chlorofluorocarbons., 7748-36-9.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts