Tang, Defu team published research in Animal Biotechnology in | 24034-73-9

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Geranylgeraniol, a precursor to geranylgeranylpyrophosphate, is an intermediate in the mevalonate pathway. Geranylgeraniol has been shown to prevent bone re-absorption, inhibition of osteoclast formation, and kinase activation in vitro. When working with statins, Geranylgeraniol can reduce the toxicity without inhibiting the cholesterol-producing effects. Geranylgeraniol has been documented to counteract the effects of fluvastatin by inhibiting activation of caspase-1 and production of IL-1. Additionally Geranylgeraniol has been found to induce apoptosis in HL-60 cells.
, 24034-73-9.

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Tang, Defu;Du, Baolong;Yan, Ruxia;Chen, Zhigang;Nian, Fang research published 《 Effect of dietary-aged maize on growth performance, nutrient utilization, and serum metabolites in broilers》, the research content is summarized as follows. In China, most maize used for animal diets is stored for long periods. We examined the effects of dietary aged maize on growth performance, nutrients utilization, and serum metabolites in broilers. A total of 270 healthy 1-day-old male Cobb broilers were assigned randomly into three treatments groups and fed maize stored for different times (24 days, M0; 18 mo, M18; 36 mo, M36). Growth performance was examined at 21 and 42 days of age. Nutrient digestibility was studied on days 18-21 and 38-41. At day 42, blood samples were collected for serum metabolite anal. Dietary aged maize significantly affected the feed to gain ratio, total starch digestibility, and apparent metabolizable energy (p < 0.05). Compared with the M0 group, 39 and 144 differential metabolites were observed in the M18 and M36 groups, resp., whereas 56 differential metabolites were identified between the M18 and M36 groups. Pathway anal. indicated that the main altered pathways were clustered into lipid metabolism in M18, and lipid and glucose metabolism in M0 and M36, resp. In conclusion, neg. effects were observed for both new harvested maize and maize stored for 36 mo; maize stored for 18 mo may improve broiler performance.

Recommanded Product: (2E,6E,10E)-3,7,11,15-Tetramethylhexadeca-2,6,10,14-tetraen-1-ol, Geranylgeraniol is a diterpenoid that is hexadeca-2,6,10,14-tetraene substituted by methyl groups at positions 3, 7, 11 and 15 and a hydroxy group at position 1. It has a role as a plant metabolite, a volatile oil component and an antileishmanial agent. It is a diterpenoid and a polyprenol.

Geranylgeraniol, a precursor to geranylgeranylpyrophosphate, is an intermediate in the mevalonate pathway. Geranylgeraniol has been shown to prevent bone re-absorption, inhibition of osteoclast formation, and kinase activation in vitro. When working with statins, Geranylgeraniol can reduce the toxicity without inhibiting the cholesterol-producing effects. Geranylgeraniol has been documented to counteract the effects of fluvastatin by inhibiting activation of caspase-1 and production of IL-1. Additionally Geranylgeraniol has been found to induce apoptosis in HL-60 cells.
, 24034-73-9.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts