In general, the hydroxyl group makes alcohols polar. Those groups can form hydrogen bonds to one another and to most other compounds. 647-42-7, formula is C8H5F13O, Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. Methanol, ethanol, and propanol are miscible in water. Butanol, with a four-carbon chain, is moderately soluble. HPLC of Formula: 647-42-7
Soykan, U.;Sert, Y.;Yildirim, G. research published 《 DFT, Molecular Docking and Drug-likeness Analysis: Acrylate molecule bearing perfluorinated pendant unit》, the research content is summarized as follows. In this study, 2-oxo-1,1-diphenyl-2-((3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl) oxy)ethyl acrylate (ODDFA) mol. was synthesized by the condensation reaction method and the detailed characterization of ODDFA was exptl. and theor. performed for the first time. As for the theor. work, mol. geometry, vibrational frequencies, chem. shifts (1H and 13C), electrochem. properties and the mol. electrostatic potential (MEP) were investigated with d. functional theory method (DFT, B3LYP) at the standard 6-311++G(d,p) level of calculation in the ground state. Moreover, mol. docking simulation and drug-likeness studies of title compound are carried out to determine the pharmacy potential for the title mol. Bond lengths and angles, the electron engagements, conjugative effect, lone pairs of electrons and possible intra-mol. charge transfer regions regarding the most favored mol. structure of the ODDFA are discussed in detail. The obtained results show that mostly all the computations and exptl. results are noted to be in a good correlation with each other. HOMO-LUMO anal. also depicts that the π-π* conjugations are concentrated on the Ph rings and carbonyl groups as well as ODDFA mol. possesses the kinetic chem. stability. As for the MEP examination, there exist both the nucleophilic and electrophilic reactive regions together over the surface of mol. thanks to the existence of both the polar and apolar functional groups in the mol. Moreover, the mol. docking studies confirm that the ODDFA compound studied have the strong potential to behave as the potent inhibitor for tyrosinase with the PDE code of 5I38. Drug-likeness anal. also reveals that the mol. possesses considerable molinspiration bioactivity.
HPLC of Formula: 647-42-7, 3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluorooctan-1-ol, also known as 1H,1H, 2H, 2H-Tridecafluoro-1-n-octanol , is a useful research compound. Its molecular formula is C8H5F13O and its molecular weight is 364.1 g/mol. The purity is usually 95%.
1H,1H, 2H, 2H-Tridecafluoro-1-n-octanol is a material used to improve nanotube composites. It is also used in the synthesis of a recyclable fluorous hydrazine carbothioate compound with NCS to catalyze the acetalization of aldehydes.
1H,1H,2H,2H-Tridecafluoro-1-n-octanol is a potent and selective halogenated hydrocarbon. It binds to DNA at the dinucleotide phosphate site, which is an important site for polymerase chain reaction (PCR) activation. 1HFN has been shown to be more effective than other halogenated hydrocarbons in vitro assays on rat liver microsomes. It has been used as an additive in wastewater treatment to remove organic contaminants and metal ions. In vivo studies have been carried out in CD-1 mice to determine the effects of 1HFN on the liver and kidneys; these studies showed no toxicological effects on these organs. 1HFN also has been shown to inhibit enzymes such as cytochrome P450 and monoamine oxidase B that are involved in drug metabolism and may lead to adverse reactions with drugs metabolized by these enzymes., 647-42-7.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts