Quality Control of 72824-04-5, In chemistry, an alcohol is a type of organic compound that carries at least one hydroxyl functional group (−OH) bound to a saturated carbon atom. 72824-04-5, name is 2-Allyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, An important class of alcohols, of which methanol and ethanol are the simplest examples, includes all compounds which conform to the general formula CnH2n+1OH.
Pan, Yu-Liang;Shao, Ying-Bo;Wang, Jie;Liu, Zhen;Chen, Li;Li, Xin research published 《 Kinetic Resolution of 2H-Azirines by Asymmetric Allylation Reactions》, the research content is summarized as follows. A practical and efficient method for kinetic resolution of azirines was achieved via asym. allylations of racemic 2H-azirines with boron allylation reagents enabled by Bi(OAc)3/chiral phosphoric acid catalysis.A broad range of azirine substrates with electron-withdrawing and electron-donating groups at the two aromatic rings, as well as the different allyl boron reagents, were well tolerated in this methodol., providing high kinetic resolution performance (with an s-factor of up to 127) under very mild reaction conditions with only 2 mol % catalyst loading. In addition, the synthetic utility of the protocol was proved by the scaled-up reaction and transformations of the product. Computational studies suggested that the various weak interactions were essential for enantioselectivity. Moreover, the effect of different metal acetates and counter anions on the reaction outcome was also interpreted by the calculations
Quality Control of 72824-04-5, Allylboronic acid pinacol ester is a useful research compound. Its molecular formula is C9H17BO2 and its molecular weight is 168.04 g/mol. The purity is usually 95%.
Allylboronic acid pinacol ester is an allylation reagent that is used to produce aldehydes from ketones. It reacts with water, yielding the desired product and formaldehyde as a byproduct. The reaction proceeds through a sequence of steps, in which the boronate ester first reacts with water to form an allylboronate ion and hydrogen gas. This intermediate then reacts with potassium t-butoxide to produce the desired allyl alcohol and potassium borohydride. Finally, the palladium complex catalyst reduces the carbonyl group of the starting material, converting it into an aldehyde. Allylboronic acid pinacol ester is commercially available as a white solid, but can also be synthesized from 2-chloro-5-pinacolylborane (pinacol) in high yield using catalytic cross coupling reactions., 72824-04-5.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts