Some low molecular weight alcohols of industrial importance are produced by the addition of water to alkenes. 24034-73-9, formula is C20H34O, Ethanol, isopropanol, 2-butanol, and tert-butanol are produced by this general method. Two implementations are employed, the direct and indirect methods. Safety of (2E,6E,10E)-3,7,11,15-Tetramethylhexadeca-2,6,10,14-tetraen-1-ol
Liu, Qi;Wang, Yu-Mei;Fu, Wen-Hao;Zhang, Ai-Hua research published 《 Gas chromatography coupled with mass spectrometry for the rapid characterization and screening of volatile oil of Euphorbia fischeriana Steud》, the research content is summarized as follows. Gas chromatog. (GC)-mass spectrometry is a powerful tool which is used in the anal. of volatile components in food and herbal medicine. Euphorbia fischeriana Steud., a traditional Chinese herb, has been used for thousands of years in China. Recently, scientists are exploring more on the pharmacol. action of E. fischeriana. However, so far, there is no information regarding the volatile constituents of E. fischeriana. Therefore, in this study, we aimed to investigate and characterize the global chem. ingredients of volatile oil of E. fischeriana under in vitro and in vivo conditions. In this study, an accurate and rapid GC combined with the mass spectrometric method and MassHunter tool were employed to identify the comprehensive constituents and explored the absorbed components in rat serum after oral administration of E. fischeriana. According to our results, a total of 28 compounds were identified via in vitro anal. by matching with the NIST database. Of them, the following 14 compounds were tentatively characterized in the serum samples: (-)-alpha-cedrene; (+/-)-sesquithuriferone; cedrol; acorenone; neocembrene; geranylgeraniol; abietatriene; abieta-7,13-diene; cembrenol; sclareol; Et linoleate; isopimara-7,15-dien-3-one; abietadienal; and abietinol. Most of the compounds identified were diterpenes and sesquiterpenes. These results might be useful in various pharmacol. and pharmacodynamic research, and the established method could offer valuable chem. information for bioactive volatile components characterization.
Safety of (2E,6E,10E)-3,7,11,15-Tetramethylhexadeca-2,6,10,14-tetraen-1-ol, Geranylgeraniol is a diterpenoid that is hexadeca-2,6,10,14-tetraene substituted by methyl groups at positions 3, 7, 11 and 15 and a hydroxy group at position 1. It has a role as a plant metabolite, a volatile oil component and an antileishmanial agent. It is a diterpenoid and a polyprenol.
Geranylgeraniol, a precursor to geranylgeranylpyrophosphate, is an intermediate in the mevalonate pathway. Geranylgeraniol has been shown to prevent bone re-absorption, inhibition of osteoclast formation, and kinase activation in vitro. When working with statins, Geranylgeraniol can reduce the toxicity without inhibiting the cholesterol-producing effects. Geranylgeraniol has been documented to counteract the effects of fluvastatin by inhibiting activation of caspase-1 and production of IL-1. Additionally Geranylgeraniol has been found to induce apoptosis in HL-60 cells.
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Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts