With respect to acute toxicity, simple alcohols have low acute toxicities. Doses of several milliliters are tolerated. 647-42-7, formula is C8H5F13O, For pentanols, hexanols, octanols and longer alcohols, LD50 range from 2–5 g/kg (rats, oral). Ethanol is less acutely toxic.All alcohols are mild skin irritants. Related Products of 647-42-7
Lampic, Alina;Parnis, J. Mark research published 《 Property Estimation of Per- and Polyfluoroalkyl Substances: A Comparative Assessment of Estimation Methods》, the research content is summarized as follows. High quality physicochem. property data are required. to accurately predict the environmental fate of per- and polyfluoroalkyl substances (PFAS). Since such data are often not available from experiments, assessing the accuracy of existing property estimation models is essential. The quality of predicted physicochem. property data for 25 PFAS was examined using COSMOtherm and EPI Suite, estimation models accessible through the USEPA CompTox Chems. Dashboard, and Linear Solvation Energy Relationships (LSER) available through the UFZ-LSER Database. Results showed COSMOtherm provided the most accurate acid dissociation constant and air-water partition ratio estimates vs. literature data. The OPEn structure-activity/property relationship apparatus (OPERA; through the CompTox Chems. Dashboard) estimated vapor pressure and dry octanol-air partition ratios which most accurately compared with other models of interest. Wet octanol-water partition ratios were comparably predicted by OPERA and EPI Suite; organic C soil coefficient and solubility were well predicted by OPERA and COSMOtherm. Perfluoroalkyl acids acid dissociation significantly affected their physicochem. properties; ionization corrections were included where applicable.
Related Products of 647-42-7, 3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluorooctan-1-ol, also known as 1H,1H, 2H, 2H-Tridecafluoro-1-n-octanol , is a useful research compound. Its molecular formula is C8H5F13O and its molecular weight is 364.1 g/mol. The purity is usually 95%.
1H,1H, 2H, 2H-Tridecafluoro-1-n-octanol is a material used to improve nanotube composites. It is also used in the synthesis of a recyclable fluorous hydrazine carbothioate compound with NCS to catalyze the acetalization of aldehydes.
1H,1H,2H,2H-Tridecafluoro-1-n-octanol is a potent and selective halogenated hydrocarbon. It binds to DNA at the dinucleotide phosphate site, which is an important site for polymerase chain reaction (PCR) activation. 1HFN has been shown to be more effective than other halogenated hydrocarbons in vitro assays on rat liver microsomes. It has been used as an additive in wastewater treatment to remove organic contaminants and metal ions. In vivo studies have been carried out in CD-1 mice to determine the effects of 1HFN on the liver and kidneys; these studies showed no toxicological effects on these organs. 1HFN also has been shown to inhibit enzymes such as cytochrome P450 and monoamine oxidase B that are involved in drug metabolism and may lead to adverse reactions with drugs metabolized by these enzymes., 647-42-7.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts