Desai, Nisheeth C.; Jadeja, Krunalsinh A.; Jadeja, Dharmpalsinh J.; Khedkar, Vijay M.; Jha, Prakash C. published their research in Synthetic Communications in 2021. The article was titled 《Design, synthesis, antimicrobial evaluation, and molecular docking study of some 4-thiazolidinone derivatives containing pyridine and quinazoline moiety》.Application In Synthesis of 3-Hydroxybenzaldehyde The article contains the following contents:
A series of 5-aryl-3-(4-oxo-2-phenylquinazolin-3(4H)-yl)-2-(pyridin-4-yl)thiazolidin-4-ones I (R = H, 3-Me, 4-F, etc.) were synthesized and evaluated for their antibacterial and antifungal activities. The title compounds showed good to excellent inhibition potency for resp. Gram-pos. bacterial strains and Gram-neg. bacterial strains. These compounds exhibited a broad spectrum of inhibitory activity. Mol. docking studies against microbial DNA gyrase sub unit B could provide valuable insights into the binding affinity of these mols. and their plausible mechanism of antimicrobial action. Most of the compounds exhibited excellent activity against bacterial and fungal strains resp. In the experimental materials used by the author, we found 3-Hydroxybenzaldehyde(cas: 100-83-4Application In Synthesis of 3-Hydroxybenzaldehyde)
3-Hydroxybenzaldehyde(cas: 100-83-4) can be used as a reactant along with ethyl acetoacetate and thiourea in the synthesis of corresponding dihydropyrimidine-2-thione (monastrol), using Yb(OTf)3 as a catalyst by Biginelli cyclocondensation reaction.Application In Synthesis of 3-Hydroxybenzaldehyde
Referemce:
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