《Selective synthesis of alkyl amines and N-vinylazoles from vinyl sulfonium salts with N-nucleophiles》 was written by Zou, Liang-Hua; Liu, Biao; Wang, Cheng; Shao, Zeyu; Zhou, Junqi; Shao, Andong; Wen, Jian. Recommanded Product: Oxetan-3-olThis research focused onvinyltetrahydrothiophenium salt amine coupling; sulfanylalkylamine preparation green chem; alkenyl amine preparation green chem. The article conveys some information:
An efficient and green method for the synthesis of various alkyl amines via the C(sp3)-S bond cleavage of vinylsulfonium salts was developed. The reaction proceeded under air atm. with a broad scope of N-nucleophiles ranging from primary and secondary alkyl and aryl amines to various N-containing heterocycles. Moreover, in the presence of a base, the reaction of vinylsulfonium salts with N-containing heterocycles at room temperature can also afford N-vinylazoles with moderate to good yields. Finally, the practicality of this protocol was demonstrated by one-pot reaction, scale-up reaction and product derivatization. In addition to this study using Oxetan-3-ol, there are many other studies that have used Oxetan-3-ol(cas: 7748-36-9Recommanded Product: Oxetan-3-ol) was used in this study.
Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.Recommanded Product: Oxetan-3-ol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts