Zhang, Wenzhi; Bie, Fusheng; Ma, Jie; Zhou, Fengyan; Szostak, Michal; Liu, Chengwei published an article in 2021. The article was titled 《Palladium-Catalyzed Decarbonylative Borylation of Aryl Anhydrides》, and you may find the article in Journal of Organic Chemistry.Safety of 4,4,5,5-Tetramethyl-2-phenyl-1,3,2-dioxaborolane The information in the text is summarized as follows:
A Pd-catalyzed base-free decarbonylative borylation of aryl anhydrides was developed. Catalyst system consisting of Pd(OAc)2/dppb enables readily available aryl anhydrides to be employed as electrophiles for the synthesis of versatile arylboronate esters via O-C(O) bond activation and decarbonylation. This method was characterized by an excellent functional group tolerance and broad substrate scope, using bench stable aryl anhydrides as aryl electrophiles in C-B bond formation. Mechanistic studies and functionalization of late-stage pharmaceutical mols. are disclosed. In the experiment, the researchers used 4,4,5,5-Tetramethyl-2-phenyl-1,3,2-dioxaborolane(cas: 24388-23-6Safety of 4,4,5,5-Tetramethyl-2-phenyl-1,3,2-dioxaborolane)
4,4,5,5-Tetramethyl-2-phenyl-1,3,2-dioxaborolane(cas: 24388-23-6) also known as boronate ester, is generally used in metal-catalyzed C-C bond formation reactions like Suzuki–Miyaura reaction.Safety of 4,4,5,5-Tetramethyl-2-phenyl-1,3,2-dioxaborolane
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