Application of 111-90-0, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 111-90-0, name is Diethylene Glycol Monoethyl Ether. This compound has unique chemical properties. The synthetic route is as follows.
To a stirred solution of DCM, diethylene glycol mono ethyl ether (21.0 ml_, 150 mmol), and triethylamine (34.7 ml_, 250 mmol) under a nitrogen atmosphere at -78 0C was added dropwise bromo acetyl bromide (17.2 ml_, 200 mmol). After stirring at -78 0C for 3 h, the reaction mixture was allowed to warm up to -20 0C and quenched by addition of water (50 ml_). The organic phase was washed with distilled water (3 x 50 ml_), saturated ammonium chloride (3 x 50 ml_), saturated sodium bicarbonate (3 x 50 ml_) and brine (2 x 50 ml_). The organic phase was then dried over magnesium sulfate, filtered and solvents removed via rotary evaporation to yield a crude product in 87 % yield. This crude product was distilled (bp 105 – 115 0C) to give a colourless liquid at RT in 71 % yield.
According to the analysis of related databases, 111-90-0, the application of this compound in the production field has become more and more popular.
Reference:
Patent; DUBLIN CITY UNIVERSITY; WO2009/24607; (2009); A1;,
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