Epifanov, Maxim; Mo, Jia Yi; Dubois, Rudy; Yu, Hao; Sammis, Glenn M. published their research in Journal of Organic Chemistry in 2021. The article was titled 《One-Pot Deoxygenation and Substitution of Alcohols Mediated by Sulfuryl Fluoride》.HPLC of Formula: 13325-10-5 The article contains the following contents:
Herein, the SO2F2-mediated alc. substitution and deoxygenation method that relies on the conversion of fluorosulfates to alkyl halide intermediates was reported. This strategy allows the expansion of SO2F2-mediated one-pot processes to include radical reactions, where the alkyl halides was exploited in the one-pot deoxygenation of primary alcs. under mild conditions (52-95% yield). This strategy enhanced the scope of substitutions to nucleophiles that are previously incompatible with one-pot SO2F2-mediated alc. activation and enables substitution of primary and secondary alcs. in 54-95% yield. Chiral secondary alcs. underwent a highly stereospecific (90-98% ee) double nucleophilic displacement with an overall retention of configuration.4-Aminobutan-1-ol(cas: 13325-10-5HPLC of Formula: 13325-10-5) was used in this study.
4-Aminobutan-1-ol(cas: 13325-10-5) is used in the synthesis of NSAIDs with anti-inflammatory properties. Also used in the synthesis of polyamine transport ligands with specificity against human cancers allowing easy access to specific cancer cells.HPLC of Formula: 13325-10-5
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts