Electric Literature of 702-23-8, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 702-23-8, name is 2-(4-Methoxyphenyl)ethanol. A new synthetic method of this compound is introduced below.
PREPARATION F 4-(3-[p-Methoxyphenyl]propyl)pyridine To a stirred solution of 3.04 g. of 2-(p-methoxyphenyl)ethanol in 10 ml. of benzene, is added dropwise, a solution of 0.72 ml. of phosphorus tribromide in 10 ml. of benzene, at ambient temperature. The mixture is then heated at 60C. for 1 hour. After being cooled to ambient temperature again, the reaction mixture is poured onto 50 g. of crushed ice. A small amount of ether is added, and then the organic phase is separated off, washed sequentially with 0.5N sodium hydroxide and water, and evaporated to dryness. This affords 2.8 g. of 2-(p-methoxyphenyl)ethyl bromide as an oil.
At the same time, in my other blogs, there are other synthetic methods of this type of compound,702-23-8, 2-(4-Methoxyphenyl)ethanol, and friends who are interested can also refer to it.
Reference:
Patent; Pfizer Inc.; US3983107; (1976); A;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts