Ma, Zhiyuan; Cunningham, Alexander J.; Zhu, X. X. published the artcile< Enzymatic Conversion of Galactose Polymers into Copolymers Containing Galactonic Acid by Glucose Oxidase>, SDS of cas: 4064-06-6, the main research area is copolymer PEG glycopolymer glucose oxidase.
Sugar oxidase can oxidize a carbohydrate substrate into an acid, but there have been no reports on the successful enzymic conversion of glycopolymers containing carbohydrate pendants. We introduced a poly(ethylene glycol) (PEG) spacer between the carbohydrate and the methacrylic units, and glucose oxidase (GOx) showed enzymic activity when the PEG spacer is sufficiently long, converting the galactose pendant into galactonic acid and yielding a copolymer. The glycopolymers with a PEG spacer showed stronger binding to the sugar-specific lectin than those without the spacer, while the binding was gradually weakened as the sugar pendants were converted to acid groups. To the best of our knowledge, this is the first example to use a hydrophilic PEG spacer to enzymically convert a substrate attached on a polymer chain. The enzymic conversion of such glycopolymers represents a useful green chem. approach to obtain copolymers based on carbohydrates.
Biomacromolecules published new progress about Enzymic oxidation. 4064-06-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H20O6, SDS of cas: 4064-06-6.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts