Pannu, Naveet; Bhatnagar, Archana published the artcile< Resveratrol: from enhanced biosynthesis and bioavailability to multitargeting chronic diseases>, Formula: C14H12O3, the main research area is review antioxidative antiinflammatory immunomodulating resveratrol bioavailability; Biosynthesis; Cardiovascular diseases; Diabetes; Neurological diseases; Pharmacokinetics; Resveratrol.
A review. Resveratrol, a phytoalexin with a wide range of pharmacol. properties is synthesized by plants in response to stress, injury, infection or UV radiations. As it is a secondary metabolite with many health promoting properties, various methods employing microorganisms and genetic manipulation of different synthetic enzymes, have been comprehensively studied to increase its production This flavonoid is extensively researched due to its pharmacol. properties such as anti-oxidative, anti-inflammatory and immuno-modulating effects. Knowledge of these properties of resveratrol has led to elaborate studies on its effect on diabetes, neurodegenerative diseases, cancer, ageing, obesity and cardiovascular diseases. At mol. level it targets sirtuin, adenosine monophosphate kinase, nuclear Factor-κB, inflammatory cytokines, anti-oxidant enzymes along with cellular processes such as angiogenesis, apoptosis, mitochondrial biogenesis, gluconeogenesis and lipid metabolism This discusses the properties of resveratrol and the different approaches of addressing the unfavorable synthesis and pharmacokinetics of this stilbene. Pre-clin. evaluations of resveratrol on diabetes mellitus, cardiovascular and neurol. diseases are elaborately discussed and the underlying pathways involved in its therapeutic activity have been given paramount importance. Following the pre-clin. studies, clin. trials on the same reveal the efficacy of resveratrol in the effective management of these diseases. This provides an intricate insight on resveratrol’s significance from a dietary component to a therapeutic agent.
Biomedicine & Pharmacotherapy published new progress about Aging, animal. 501-36-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C14H12O3, Formula: C14H12O3.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts