Okuda, Yuta; Nagaoka, Masahiro; Yamamoto, Tetsuya published the artcile< Bulky N-Heterocyclic-Carbene-Coordinated Palladium Catalysts for 1,2-Addition of Arylboron Compounds to Carbonyl Compounds>, Safety of Triphenylmethanol, the main research area is nitrogen heterocyclic carbene pentanylaniline cyclometallated palladium complex preparation catalyst; primary secondary tertiary alc preparation; arylboronic acid boronate aldehyde ketone addition.
The synthesis of primary, secondary, and tertiary alcs. by the 1,2-addition of arylboronic acids or boronates to carbonyl compounds, including unactivated ketones, using novel bulky yet flexible N-heterocyclic carbene (NHC)-coordinated 2,6-di(pentan-3-yl)aniline (IPent)-based cyclometallated palladium complexes (CYPs) as catalysts is reported. The PhS-IPent-CYP-catalyzed reactions are efficient at low catalyst loadings (0.02-0.3 mol% Pd), and the exceptional catalytic activity for 1,2-addition is attributed to the steric bulk of the NHC ligand. These reactions can yield a wide range of functionalized benzylic alcs. that are difficult to synthesize by classical protocols using highly active organomagnesium or lithium reagents.
ChemCatChem published new progress about 1,2-Addition reaction. 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Safety of Triphenylmethanol.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts