Rashidnejad, Hamid; Kordi, Mohammad Anvar; Pesyan, Nader Noroozi; Allahyari-devin, Maryam; Frashchi, Alireza Hajabbas; Ramezanitaghartapeh, Mohammad published the artcile< Cascade Synthesis of 1,4-Butanediol Monomesylate Glycoconjugates: Anticancer Candidates for Leukemia>, Formula: C6H12O6, the main research area is butanediol monomesylate glycoconjugate antitumor agent leukemia.
Acascade synthesis protocol for glycosides of 1,4-butanediol monomesylate, as anticancer drug candidates, is proposed. All obtained compounds are characterized by FT-IR, 1H and 13C NMR spectroscopy technique after separation by column chromatog. Cytotoxicity of the obtained glucosides and galactosides of 1,4-butanediol monomesylate on K562 human erythroleukemia cell line and normal peripheral blood mononuclear cells (PBMCs) is also investigated. Compared to the commerical anticancer drugs such as busulfan and doxorubicin, these compounds indicate promising results against the test cells. It is suggested that these new anticancer agents can be a potential replacement for the current drugs since they have relatively convenient synthetic procedure and higher effectiveness.
Pharmaceutical Chemistry Journal published new progress about Antitumor agents. 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Formula: C6H12O6.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts