Vezse, Panna; Benda, Bianka; Fekete, Andras; Golcs, Adam; Toth, Tunde; Huszthy, Peter published the artcile< Covalently Immobilizable Tris(Pyridino)-Crown Ether for Separation of Amines Based on Their Degree of Substitution>, Name: Triphenylmethanol, the main research area is amine separation trispyridinocrown ether mol recognition; biogenic amine; crown ether; molecular recognition; separation.
A great number of biol. active compounds contain at least one amine function. Appropriate selectivity can only be accomplished in a few cases upon the substitution of these groups, thus functionalization of amines generally results in a mixture of them. The separation of these derivatives with very similar characteristics can only be performed on a preparative scale or by applying pre-optimized HPLC methods. A tris(pyridino)-crown ether was designed and synthesized for overcoming these limitations at a mol. level. It is demonstrated, that this selector mol. is able to distinguish protonated primary, secondary and tertiary amines by the formation of reversible complexes with different stabilities. This degree of substitution-specific mol. recognition of amines opens the door to develop separation processes primarily focusing on the purification of biol. active compounds in a nanomolar scale.
Molecules published new progress about Crown ethers Role: SPN (Synthetic Preparation), PREP (Preparation). 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Name: Triphenylmethanol.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts