《Synthesis and antioxidant properties of some new thiazolyl coumarin derivatives》 was published in Green Chemistry Letters and Reviews in 2020. These research results belong to Bensalah, Donia; Mnasri, Aziza; Chakchouk-Mtibaa, A.; Mansour, Lamjed; Mellouli, L.; Hamdi, Naceur. COA of Formula: C7H6O2 The article mentions the following:
A three-component one-pot synthesis of new thiazolyl coumarins I (R = Ph, 4-O2NC6H4, 3-HOC6H4, etc.) was carried out by condensing 3-acetyl-4-hydroxycoumarin, benzaldehydes RCHO, thiourea and ammonium acetate at reflux in di-Me carbonate. The optimization details of the developed novel protocol are described. In addition, these compounds were also synthesized via another route in two steps. High atom-economy, excellent yields, simple procedure and mild reaction conditions are the important features of this one-pot protocol. The chem. structures of the newly synthesized compounds I were elucidated using IR, 1H NMR, 13C NMR spectroscopy. All the compounds I were screened for their antioxidant activities.3-Hydroxybenzaldehyde(cas: 100-83-4COA of Formula: C7H6O2) was used in this study.
3-Hydroxybenzaldehyde(cas: 100-83-4) can be used as a reactant along with ethyl acetoacetate and thiourea in the synthesis of corresponding dihydropyrimidine-2-thione (monastrol), using Yb(OTf)3 as a catalyst by Biginelli cyclocondensation reaction.COA of Formula: C7H6O2
Referemce:
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