Lv, Chunrong; Larbi, Allai; Wu, Guoquan; Hong, Qionghua; Quan, Guobo published the artcile< Improving the quality of cryopreserved goat semen with a commercial bull extender supplemented with resveratrol>, Safety of (E)-5-(4-Hydroxystyryl)benzene-1,3-diol, the main research area is resveratrol semen extender cryopreservation goat; Antioxidant; Cryopreservation; Goats; Resveratrol; Semen.
The purpose of the current study was to evaluate the effects of resveratrol (RSV) on the quality of frozen-thawed goat sperm. Semen samples from four bucks were divided into five aliquots and diluted with a com. bull semen extender containing: no antioxidant (RSV-0, control), 10μM RSV (RSV-10), 50μM RSV (RSV-50), 100μM RSV (RSV-100) and 250μM RSV (RSV-250). After thawing, sperm motility, abnormal morphol., membrane and acrosome integrity, mitochondrial activity, phosphatidylserine (PS) distribution, and oxidative stress were evaluated. The results indicated that in comparison with the control, when the concentration of RSV was 10 or 50μM, the total motility, progressive motility, membrane and acrosome integrity, and mitochondrial activity of post-thaw spermatozoa was greater (P < 0.05). Addnl., the use of extenders containing RSV-10 or RSV-50 resulted in a greater percentage of viable spermatozoa as compared to the other groups (P < 0.05). Importantly, there were more viable spermatozoa (49.61 ± 0.61%) and less non-viable spermatozoa (49.16 ± 1.01%) in the RSV-50 group compared to the other extenders (P < 0.05). Furthermore, the use of the extenders containing RSV-10 and -50 resulted in a reduction in ROS production in frozen-thawed spermatozoa as compared to the control (P < 0.05). There, however, was no difference among extenders for abnormal morphol. and PS distribution. In conclusion, supplementation with RSV, at a concentration of 10 or 50μM in the semen extender, can improve the post-thaw goat sperm quality, which may occur as a consequence of inhibition of ROS generation. Animal Reproduction Science published new progress about Acrosome. 501-36-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C14H12O3, Safety of (E)-5-(4-Hydroxystyryl)benzene-1,3-diol.
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