Mondal, John; Borah, Parijat; Modak, Arindam; Zhao, Yanli; Bhaumik, Asim published the artcile< Cu-Grafted Functionalized Mesoporous SBA-15: A Novel Heterogeneous Catalyst for Facile One-Pot Three-Component C-S Cross-Coupling Reaction of Aryl Halides in Water>, Computed Properties of 4396-13-8, the main research area is copper grafted SBA15 coupling aryl halide benzyl bromide thiourea; aryl alkyl thioether synthesis.
A highly ordered 2D hexagonal Cu-grafted functionalized mesoporous SBA-15 (Cu-PIF-SBA-15) has been designed through postsynthetic modification of mesoporous SBA-15. Surface functionalization technique has been employed to synthesize -NH2 functionalized mesoporous SBA-15 material. Schiff base condensation of this -NH2 functionalized SBA-15 with phloroglucinol dialdehyde leads to the formation of PIF-SBA-15. Reaction of PIF-SBA-15 with Cu-(OAc)2·H2O in ethanol under reflux leads to the formation of Cu-PIF-SBA-15 catalyst. This Cu-PIF-SBA-15 catalyst exhibits excellent catalytic activity in a one-pot three-component C-S coupling reaction for a diverse range of aryl halides (bromide and chloride) with thiourea and benzyl bromide in aqueous medium to offer aryl alkyl thioether in very good yields [e.g., 4-bromoanisole + thiourea + benzyl bromide → 4-MeOC6H4SCH2Ph (79%)]. Due to the strong binding ability of the imine-N and phenolic-OH functional groups present in the phloroglucinol diimine moiety of the framework, the anchored Cu-(II) could not leach out from the surface of the mesoporous catalyst during the course of reaction, and it has been observed that six repetitive reaction cycles could not cause any appreciable loss in the catalytic activity of this material.
Organic Process Research & Development published new progress about Aryl bromides Role: RCT (Reactant), RACT (Reactant or Reagent). 4396-13-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H6O5, Computed Properties of 4396-13-8.
Referemce:
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Alcohols – Chemistry LibreTexts