Zhang, Si-Xuan; Ding, Yan; Wang, Jun-Jie; Shen, Chuanji; Zhou, Xiaocong; Chu, Xue-Qiang; Ma, Mengtao; Shen, Zhi-Liang published the artcile< Titanium(IV)-Mediated Ring-Opening/Dehydroxylative Cross-Coupling of Diaryl-Substituted Methanols with Cyclopropanol Derivatives>, Safety of Triphenylmethanol, the main research area is diaryl ester preparation; ethoxycyclopropoxy trimethylsilane diaryl methanol ring opening dehydroxylative cross coupling.
A titanium(IV)-mediated ring-opening/dehydroxylative cross-coupling of diaryl-substituted methanols R(R1)C(OH)R2 (R = Ph, 2-methylphenyl, 4-iodophenyl, naphthalen-1-yl, etc.; R1 = H, Ph, 4-methylphenyl, 4-chlorophenyl; R2 = Ph, 4-methoxyphenyl, 4-fluorophenyl, etc.) with a (1-ethoxycyclopropoxy)trimethylsilane was developed. The reactions proceeded efficiently to provide synthetically useful γ,γ-diaryl esters R(R1)C((CH2)2C(O)OCH2CH3)R2 in moderate to good yields, which could be applied to the functionalization of complex mols. I and II derived from bioactive fenofibrate and isoxepac and the synthesis of a precursor of Zoloft III.
Journal of Organic Chemistry published new progress about Aralkyl alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Safety of Triphenylmethanol.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts